The highly anticipated UFC 334 event will feature a women's bantamweight title clash between current champion Kayla Harrison and former two-division UFC champion Amanda Nunes. This co-main event has been rescheduled for November 14, 2026, at Madison Square Garden in New York City after initially being set for January 2026 was delayed due to Harrison’s neck surgery. Harrison, known for her two Olympic judo gold medals and rapid climb in MMA, will defend her title against the legendary Nunes, who retired in 2023 but has made a comeback specifically for this fight.

Betting odds for the Harrison vs. Nunes fight have evolved significantly. Initially, Harrison was a strong favorite at -300 against Nunes' +247 odds. However, as the fight date approaches, those odds have tightened, with Harrison now at -180 and Nunes at +153, indicating increased confidence from bettors and bookies in Nunes’s chances despite Harrison’s momentum. This shift reflects the high-level competition and stature of both fighters in the MMA world.

Kayla Harrison has a decorated MMA background, starting her career with the Professional Fighters League (PFL) in 2018, compiling a record of 19-1 before signing with the UFC in January 2024. She quickly made an impact in the UFC bantamweight division, capturing the title in June 2025 with a submission win over Julianna Pena. Her extensive experience in judo and an impressive winning streak showcase her as a formidable champion in the 135-pound weight class.

Amanda Nunes, widely regarded as one of the greatest female fighters in MMA history, brings an illustrious resume to UFC 334. After debuting with the UFC in 2013, she dominated for nearly a decade, holding both bantamweight and featherweight titles simultaneously before retiring as the reigning champion in 2025. Known for her knockout power and victories over top competitors like Cris Cyborg and Ronda Rousey, Nunes is now 38 years old and motivated to reclaim her spot at the top, making this bout a landmark event in women's MMA.