PNOĒ, a startup based in Malden, Massachusetts with operations in Athens, Greece, is launching a new version of its breath-analyzing mask called the PNOĒ 2.0 on October 1. The device measures oxygen consumption and carbon dioxide exhalation to provide insights into metabolic markers like VO₂ max, resting metabolic rate, and metabolic flexibility. Unlike its previous model, the PNOĒ 2.0 allows users to administer the test themselves in about eight minutes without the need for trained operators, making it accessible for gyms and potentially pharmacies.

Metabolic testing through breath analysis has been an established method to gauge fitness, especially VO₂ max, but traditionally required bulky lab equipment and expert supervision. PNOĒ’s innovation is to deliver lab-grade accuracy in a portable, sleek device supported by software that interprets data to offer personalized fitness and nutrition advice. The mask’s components can be separated so multiple individuals can share the main hardware while keeping their own masks, addressing hygiene concerns especially in post-pandemic settings.

PNOĒ primarily markets the device to businesses such as Equinox fitness clubs, Four Seasons hotels, Red Bull, the NBA, and medical groups like Mount Sinai Health System. Clients subscribe to the service, which bundles the hardware, software, training, and marketing materials. About 85% of its business is in the U.S., but the company is expanding to Europe, Latin America, and Asia. Having raised approximately $22 million, including an $11 million round, PNOĒ recently became profitable and is planning a Series B funding round within a year to fuel further growth.

Although the PNOĒ 2.0 provides detailed metabolic data useful for wellness and longevity, it is not FDA-cleared and does not offer medical diagnoses or recommendations. The company is exploring how its growing data could help flag health issues in the future but estimates that such clinical applications remain years away due to regulatory hurdles. For now, PNOĒ positions itself as a wellness tool helping people optimize training and nutrition by understanding their body's metabolic profile.